International Illness Outbreaks: A 2025 Snapshot and Implications for the U.S.

Illness Nation Area* Major Class for Illness/Transmission Variety of Circumstances/Deaths (as of date) Acute febrile sickness Democratic Republic of the Congo Sub-Saharan Africa Not relevant 1,318 suspected circumstances, inc. 53 deaths (as of Feb. 25) Anthrax Democratic Republic of the Congo Sub-Saharan Africa Direct contact an infection 17 suspected circumstances, inc. 1 demise (as of April 30) Thailand East Asia and the Pacific 5 confirmed circumstances, inc. 1 demise (as of May 28) Uganda Sub-Saharan Africa 15 confirmed circumstances, inc. 2 deaths (as of March 30) Avian Influenza Cambodia East Asia and the Pacific Respiratory an infection Cambodia: 11 confirmed circumstances, inc. 6 deaths (as of July 1)
Mexico: 1 confirmed case, inc. 1 demise (as of April 2) Mexico Western Hemisphere Chapare hemorrhagic fever Bolivia Western Hemisphere Direct contact an infection 1 confirmed case, inc. 1 demise (as of Jan. 13) Chikungunya Key international locations:
Bangladesh South and Central Asia Vector-borne an infection International overview: 445,271 (263,592 suspected and 181,679 confirmed) circumstances, inc. 155 deaths (as of Sept. 30)
Indian Ocean international locations: knowledge not supplied (as of Sept. 5)
Bolivia: knowledge not supplied (as of June 26)
Cuba: knowledge not supplied (as of Sept. 26)
La Réunion and Mayotte (France): in La Réunion, over 47,500 confirmed circumstances, however greater than 170,000 consultations for suspected chikungunya, and not less than 12 deaths, with extra suspected; in Mayotte, 116 circumstances (as of May 4) Bolivia Western Hemisphere China East Asia and the Pacific Cuba Western Hemisphere Kenya Sub-Saharan Africa La Réunion and Mayotte (France) Sub-Saharan Africa Madagascar Sub-Saharan Africa Somalia Sub-Saharan Africa Sri Lanka South and Central Asia Cholera Afghanistan South and Central Asia Meals-/waterborne an infection International overview: 489,452 cholera/Acute Watery Diarrhea circumstances; 6,155 deaths (as of Sept. 26; earlier alert) Angola Sub-Saharan Africa Bangladesh South and Central Asia Burundi Sub-Saharan Africa Chad Sub-Saharan Africa Cote d’Ivoire Sub-Saharan Africa Democratic Republic of the Congo Sub-Saharan Africa Ethiopia Sub-Saharan Africa Ghana Sub-Saharan Africa Haiti Western Hemisphere India South and Central Asia Iraq Close to East Kenya Sub-Saharan Africa Malawi Sub-Saharan Africa Mozambique Sub-Saharan Africa Myanmar East Asia and the Pacific Namibia Sub-Saharan Africa Nepal South and Central Asia Niger Sub-Saharan Africa Nigeria Sub-Saharan Africa Pakistan South and Central Asia Philippines East Asia and the Pacific Republic of the Congo Sub-Saharan Africa Rwanda Sub-Saharan Africa Somalia Sub-Saharan Africa South Sudan Sub-Saharan Africa Sudan Sub-Saharan Africa Tanzania Sub-Saharan Africa Thailand East Asia and the Pacific Togo Sub-Saharan Africa Uganda Sub-Saharan Africa Yemen Close to East Zambia Sub-Saharan Africa Zimbabwe Sub-Saharan Africa Dengue United States of America Western Hemisphere Vector-borne an infection Outbreaks in varied areas (as of July 29); 2,560 domestically acquired circumstances (as of Sept. 25) Ebola virus disease (EVD) (inc. Sudan virus disease, SVD) Democratic Republic of the Congo

Uganda

Sub-Saharan Africa Direct contact an infection EVD: 64 suspected (53 confirmed and 11 possible) circumstances, inc. 43 deaths (as of Oct. 5; earlier alert)

SVD: 14 circumstances – 12 confirmed, 2 possible – inc. 4 deaths – 2 confirmed, 2 possible (as of April 26)

Invasive meningococcal disease Saudi Arabia Close to East Direct contact an infection 17 circumstances (as of April 11) Marburg virus disease  Tanzania Sub-Saharan Africa Direct contact an infection 10 suspected (2 confirmed, 8 possible) circumstances, inc. 10 deaths (as of March 12) Measles Argentina Western Hemisphere Respiratory an infection Area of the Americas (inc. United States of America): 10,139 confirmed circumstances, inc. 18 deaths (as of Aug. 8; earlier alert)
Morocco: greater than 25,000 suspected circumstances, inc. 13,706 confirmed circumstances and 184 deaths, from Oct. 2023 via April 13, 2025 (as of May 13)
United States of America: 1,544 circumstances, inc. 3 deaths (as of Sept. 30) Belize Western Hemisphere Bolivia Western Hemisphere Brazil Western Hemisphere Canada Western Hemisphere Costa Rica Western Hemisphere Mexico Western Hemisphere Morocco Close to East Paraguay Western Hemisphere Peru Western Hemisphere United States of America Western Hemisphere Middle East respiratory syndrome (MERS) coronavirus Saudi Arabia Close to East Respiratory an infection 9 confirmed circumstances, inc. 2 deaths (as of April 21) Mpox Key international locations:
Burundi
Democratic Republic of the Congo
Kenya
Rwanda
Sierra Leone
Uganda Sub-Saharan Africa Direct contact an infection Global overview: 38,671 confirmed circumstances, inc. 163 deaths (as of Aug. 31; earlier alert) Nipah virus Bangladesh
India South and Central Asia Direct contact an infection Bangladesh: 4 confirmed circumstances, inc. 4 deaths (as of Aug. 29)
India: 4 confirmed circumstances, inc. 2 deaths (as of July 12) Oropouche virus disease Key international locations:
Brazil
Panama Western Hemisphere Vector-borne an infection Information not supplied (as of July 14); Americas Area overview: 12,786 confirmed circumstances (as of July 27) Rabies Timor-Leste East Asia and the Pacific Direct contact an infection 4 confirmed circumstances, inc. 4 deaths (as of June 17) Rift Valley Fever Senegal Sub-Saharan Africa Vector-borne an infection Information not supplied (as of Oct. 10) Variant Poliovirus (i.e., circulating vaccine-derived poliovirus of three varieties: cVDPV1, cVDPV2, cVDPV3) cVDPV1:
Algeria Close to East Meals-/waterborne an infection cVDPV1 world overview: 2 circumstances of acute flaccid paralysis (as of Oct. 6)
 
cVDPV2 world overview: 146 circumstances of acute flaccid paralysis (as of Oct. 6)
 
cVDPV3 world overview: 5 circumstances of acute flaccid paralysis (as of Oct. 6) Democratic Republic of the Congo Sub-Saharan Africa cVDPV2:
Angola Sub-Saharan Africa Benin Sub-Saharan Africa Burkina Faso Sub-Saharan Africa Central African Republic Sub-Saharan Africa Chad Sub-Saharan Africa Djibouti Sub-Saharan Africa Ethiopia Sub-Saharan Africa Niger Sub-Saharan Africa Nigeria Sub-Saharan Africa Papua New Guinea East Asia and the Pacific Somalia Sub-Saharan Africa Sudan Sub-Saharan Africa Yemen Close to East cVDPV3:
Cameroon Sub-Saharan Africa Chad Sub-Saharan Africa Guinea Sub-Saharan Africa Yellow fever  Bolivia
Brazil
Colombia
Ecuador
Peru Western Hemisphere Vector-borne an infection 235 confirmed circumstances, inc. 96 deaths (as of May 25; earlier alert) Zika virus disease India South and Central Asia Vector-borne an infection 151 circumstances in 2024 (as of Jan. 29) Be aware: * Areas replicate these utilized by the U.S. State Division; Close to East consists of the Center East and North Africa. Illness outbreaks as recognized and outlined by the next authoritative sources: WHO, CDC, and GPEI; not an exhaustive listing of outbreaks globally. As of Oct. 10, 2025. Doesn’t embrace illnesses corresponding to COVID-19, wild poliovirus, and seasonal influenza the place there haven’t been sudden ranges of circumstances and deaths this 12 months.

Sources: WHO, Disease Outbreak News, Situation Reports, and Rapid Risk Assessment Reports; CDC, Outbreak webpage; CDC, Travel Notices webpage; GPEI, Polio This Week.